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Study shows hemp compounds prevent coronavirus from entering human cells

Laboratory research is a collaboration of researchers at OHSU, Oregon State University

“The study’s implication is that some hemp-based consumer products have the potential to prevent as well as treat infection from the novel coronavirus,” said senior author Fikadu Tafesse, Ph.D., assistant professor of molecular microbiology and immunology in the OHSU School of Medicine. (Getty Images)

New research reveals compounds in hemp demonstrate an ability to prevent the virus that causes COVID-19 from entering human cells.

The study, published in the Journal of Natural Products, was a collaboration between scientists at Oregon Health & Science University and Oregon State University.

The laboratory study used chemical screening techniques to discover that a pair of distinct cannabinoid acids in hemp — known as cannabigerol acid, or CBGA, and cannabidiolic acid, or CBDA — bind to the SARS-CoV-2 spike protein, blocking a critical step in the process the virus uses to infect people.

Fikadu Tafesse, Ph.D. (OHSU)

“This is a lab study, so it hasn’t been tested clinically,” said senior author Fikadu Tafesse, Ph.D., assistant professor of molecular microbiology and immunology in the OHSU School of Medicine. “However, the study’s implication is that some hemp-based consumer products have the potential to prevent as well as treat infection from the novel coronavirus.”

Known scientifically as Cannabis sativa, hemp is a source of fiber, food, and animal feed. Hemp extracts and compounds are also added to cosmetics, body lotions, and dietary supplements.

The study was led by Richard van Breeman, Ph.D., a researcher with Oregon State’s Global Hemp Innovation Center, College of Pharmacy, and Linus Pauling Institute.

In addition to Tafesse and van Breeman, co-authors include Ruth Muchiri of Oregon State, along with Timothy Bates, Jules Weinstein, Hans Leier, and Scotland Farley of OHSU.

For more information, see the news release from Oregon State University: https://today.oregonstate.edu/news/oregon-state-research-shows-hemp-compounds-prevent-coronavirus-entering-human-cells

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What Are the Benefits of CBD?

More than 60 percent of CBD users were taking it for anxiety, according to a survey of 5,000 people. Does it help?

By Dawn MacKeen

The CBD industry is flourishing, conservatively projected to hit $16 billion in the United States by 2025. Already, the plant extract is being added to cheeseburgers, toothpicks and breath sprays. More than 60 percent of CBD users have taken it for anxiety, according to a survey of 5,000 people, conducted by the Brightfield Group, a cannabis market research firm.Chronic pain, insomnia and depression follow behind. Kim Kardashian West, for example, turned to the product when “freaking out” over the birth of her fourth baby. The professional golfer Bubba Watson drifts off to sleep with it. And Martha Stewart’s French bulldog partakes, too.

What is CBD?

Cannabidiol, or CBD,is the lesser-known child of the cannabis sativaplant; its more famous sibling, tetrahydrocannabinol, or THC, is the active ingredient in pot that catapults users’ “high.” With roots in Central Asia, the plant is believed to have been first used medicinally — or for rituals — around 750 B.C., though there are other estimates too.

Cannabidiol and THC are just two of the plant’s more than 100 cannabinoids. THC is psychoactive, and CBD may or may not be, which is a matter of debate. THC can increase anxiety; it is not clear what effect CBD is having, if any, in reducing it. THC can lead to addiction and cravings; CBD is being studied to help those in recovery.

Cannabis containing 0.3 percent or less of THC is hemp. Although last year’s Farm Bill legalized hemp under federal law, it also preserved the Food and Drug Administration’s oversight of products derived from cannabis.

What are the claims?

CBD is advertised as providing relief for anxiety, depression and post-traumatic stress disorder. It is also marketed to promote sleep. Part of CBD’s popularity is that it purports to be “nonpsychoactive,” and that consumers can reap health benefits from the plant without the high (or the midnight pizza munchies).

Just as hemp seedlings are sprouting up across the United States, so is the marketing. From oils and nasal sprays to lollipops and suppositories, it seems no place is too sacred for CBD. “It’s the monster that has taken over the room,” Dr. Brad Ingram, an associate professor of pediatrics at the University of Mississippi Medical Center, said about all the wild uses for CBD now. He is leading a clinical trial into administering CBD to children and teenagers with drug-resistant epilepsy.

Image, person applying hemp oil lotion to skin

CBD Skincare Interest is Rising Fast: What’s the Future of Cannabidiol for Skin Health Look Like?

Since cannabidiol (CBD) was reintroduced as having potential health benefits, the areas that it appears to excel in include pain relief, reduction in anxiousness and attaining a calmer self. The key property in making the previously mentioned benefits a possibility is CBD’s ability to rid inflammation.

As the industry continues to mature, more and more skincare solutions are being infused with CBD and other cannabis’ compounds. With this in mind, curiosity is surely enticed, as consumers now have to assess its true effectiveness.

In a recent post shared by CBD Snapshot, the overall potential of CBD has been explained with respect to skincare. Turns out, it does in fact make a positive difference, however, consumers have been warned to be cautious of their resources.

CBD’s Anti-Inflammatory Properties Creates a Win-win Situation Once Again!
The news outlet referenced a board-certified dermatologist, who argued for the use of CBD for skin health. According to Dr. Jeanette, CBD can be effective in both beauty and skin care because of the very same anti-inflammatory properties that initially helped it to secure a spotlight.

Here’s an extract as to why the latter is so:

“Cannabinoid receptors have been discovered in keratinocytes, or skin cells, and other parts of the skin such as the sebaceous glands, hair follicles, small nerves and immune cells. CBD works on them as part of the skin’s endocannabinoid system.”

Dr. Robert Dellavalle, University of Colorado School of Medicine’s dermatology professor and a co-author of the 2017 study, has noticed how quickly the CBD industry has been developing and is somewhat fearful of consumers’ belief that all skin conditions can be resolved with its use. However, he does not question its general potential, adding that, “I think there’s a lot of promise.”