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How Hemp/CBD Changed Medicine

Hemp/CBD & Your Health/Wellness

Here at Native Roots Hemp we spend most of our time helping guests better understand the endocannabinoid system and how our organically grown Wisconsin hemp helps the body remain in a more balanced state of being.

But sometimes, others can explain it even better! The article below talks about the Endocannabinoid System and it’s profound effects on the human body.

Hemraj, Dipak. “The Discovery of the Endocannabinoid System: How It’s Changed Medicine.” Cannabis Science, Leafwell.com, April 16, 2018, leafwell.com

It has been written or said in many places, but it is something that needs to be reiterated: had cannabis not become such a maligned plant, Raphael Mechoulam and his team would be awarded the Nobel Prize for the discovery of the endocannabinoid system (ECS). In fact, there are several researchers in the field of endocannoids and phytocannabinoids who would be worthy of such a prize. Thankfully, they have at least been awarded a multitude of other prizes, so we can be assured that there is at least some sense in the world. After all, “If viagra can win the Nobel Prize, why not cannabis?” (Please watch The Scientist to get this reference.)

Endocannabinoid system; ECS; CB1 receptors; CB2 receptors

These scientists have won so many prizes for a good reason; and that reason is because, in discovering the ECS, they’ve changed the way we look at the human body and medicine. Many used to believe that targeting one receptor using one highly purified drug was necessary, but the discovery of the ECS has changed their mind. Nowadays, much of the talk around developing safe pharmaceuticals concerns itself with the ECS and multi-modal treatments. In some cases, learning more about the medical properties of cannabis has made us better doctors.

Indeed, so significant is the discovery of cannabinoids and the endocannabinoid system, that it may help us answer one of life’s most fundamental questions: “How and why are we here?” This is because cannabinoids play a crucial role in the beginnings of life. To quote the Abstract from ‘The endocannabinoid-CB1 receptor system in pre- and postnatal life’:

“Recent research suggests that the endogenous cannabinoids (“endocannabinoids”) and their cannabinoid receptors have a major influence during pre- and postnatal development.

First, high levels of the endocannaboid anandamide and cannabinoid receptors are present in the preimplantation embryo and in the uterus, while a temporary reduction of anandamide levels is essential for embryonal implantation. In women accordingly, an inverse association has been reported between fatty acid amide hydrolase (the anandamide degrading enzyme) in human lymphocytes and miscarriage.

Second, CB1 receptors display a transient presence in white matter areas of the pre- and postnatal nervous system, suggesting a role for CB1 receptors in brain development.

Third, endocannabinoids have been detected in maternal milk and activation of CB1 receptors appears to be critical for milk sucking by newborn mice, apparently activating oral–motor musculature.

Fourth, anandamide has neuroprotectant properties in the developing postnatal brain. Finally, prenatal exposure to the active constituent of marihuana (Δ9-tetrahydrocannabinol) or to anandamide affects prefrontal cortical functions, memory and motor and addictive behaviors, suggesting a role for the endocannabinoid CB1 receptor system in the brain structures which control these functions.

Further observations suggest that children may be less prone to psychoactive side effects of Δ9-tetrahydrocannabinol or endocannabinoids than adults. The medical implications of these novel developments are far reaching and suggest a promising future for cannabinoids in pediatric medicine for conditions including “non-organic failure-to-thrive” and cystic fibrosis.”

Sprouting plant; new life; plant growing.
Picture from https://www.flickr.com/photos/mr_t_in_dc/5057059458; Picture by “Mr.TinDC”.

To break that down for you:

  • The body’s own version of THC, anandamide, is necessary for human life to happen in the first instance.
  • Cannabinoid receptors are necessary for brain development.
  • Endocannabinoids have been discovered in the maternal milk of mice, and there is no reason to believe that other mammals’ milk is not the same.
  • Anandamide protects the brains of newborns.
  • Prenatal exposure to THC or anandamide affects memory, motor and addictive behaviors, and prefrontal cortical functions.

Some theorize that children may actually be less prone to the psychoactive effects of THC! Though there is no definitive evidence behind this, the logic seems to be that, due to the high amounts of anandamide in children, THC may not affect them in the same way it affects adults! This is one more reason given as to why cannabinoids may be an excellent treatment method for children.

However, we are sceptical of this claim, as cannabinoids play a massive role in the development of the brain during childhood and teenage years, and introducing phytocannabinoids without medical supervision during such a sensitive period may cause potential health problems, in particular mental health. There is significant research suggesting that those aged under 25 are actually more sensitive to THC, as their brains are developing. As for CBD, as it is a cannabinoid that does not have any affinity for CB1 or CB2 receptors, it is unlikely to have the effects THC has. Still, we do not know for sure precisely what sort of effect has long-term. CBD still has a physiological effect, after all.

Those who need cannabinoids for a particular health condition, they are still a potentially valid treatment regardless of age. We must also ask ourselves, “Why don’t we treat many other drugs and medications the same way and see what effect they have on the brains of children?” After all, many children are prescribed much harsher drugs than THC when they suffer from serious conditions.

Chemical structure anandamide; anandamide; THC; anandamide THC; skeletal anandamide; endocannabinoid
Anandamide. Picture from: https://commons.wikimedia.org/wiki/File:Anandamide_skeletal.svg

 

 

 

 

 

 

 

 

 

 

 

Now, we don’t know about you, but this sort of thing gets us excited, and we’d be surprised if anyone doesn’t get as excited as we are about such research. Cannabinoids being one of the reasons why life exists? This is the sort of talk that belongs in stoner circles. Yet at least one of those circles must have the spirit of Carl Sagan and other prominent now sadly-passed scientists possessing them, as that talk may just well be true!

Now, not only do cannabinoids seem to have a massive role to play in the beginnings of life, but it may also perform an immensely important part in the continuation of it as well. Cannabinoids are intimately involved in homeostasis – the “checks and balances” that keep the body and its physiological processes in equilibrium. Anandamide is hugely important for maintaining immunological health in the gut. Learning about endocannabinoids and endocannabinoid has given us a greater understanding of immune regulation, and the advances made in cannabinoid pharmacology have given us a whole new range of therapeutic targets. In fact, the ECS has potentially given us an entirely new branch of therapies. The reason why cannabis may be useful for so many conditions is because an “out-of-tune” ECS is implicated in many disease states.

Infinity symbol; cannabis leaves; cannabis; hemp; infinity symbol made from marijuana leaves.
Picture from https://pixabay.com/en/marijuana-drugs-cannabis-drug-hemp-2766323/

That cannabinoids may make up the constituents of life is nothing short of an outstanding discovery. It is almost surprising that we have only just discovered it just over two-and-a-half decades ago. The ECS is so complex that we have barely just begun to scratch the surface on what it does and how we can modulate it. There is still lots more to be done, There is actually lots to be discussed here, and in some ways the way we treat the cannabis plant has asked a some questions that shake some of the philosophical underpinnings of medicine. “How do we ensure the cure isn’t as bad and dangerous as the disease we’re trying to treat?” “Why do we prescribe things that are much worse than cannabis, especially when sometimes the evidence is shaky at best?” “Are there ways we can treat a condition without the need for invasive surgery and/or harsh pharmaceutical drugs?” Who knows? One day, many of the medicines at your local pharmacist may be cannabinoid- and/or terpenoid- based!

Caffé Tlazo Launches Hemp Infused Menu

Adding some cannabinoids to your daily routine.

With so many of our natural food derived nutrients stripped away these days (whether from stripped soil or processed foods), we’re excited to announce that Caffé Tlazo in Algoma, WI is bringing them back with hemp infused teas, coffee and smoothies! With about 150 phytocannabinoids in the hemp plant, Native Roots Hemp products take advantage of far more than just CBD. It’s time you get ALL the benefits of full-spectrum, organically grown, Wisconsin hemp!

Jenelle Glime from Caffé Tlazo invites you to the healthy side of hemp with the newest addition of hemp-infused goodies to boost those CB1 and CB2 receptors. Keep your Endocannabinoid System in a healthy state of balance.

Why should you consider HEMP in your diet?

Because of your Endocannabinoid System, that’s why. This system acts like a message center that communicates with the CB1 and CB2 receptors found in the central nervous system (CB1 receptors) and peripheral organs like immune cells (CB2 receptors). The phyto-nutrients that come from the hemp plant are known as phyto-cannabinoids. These positively interact with the CB1 and CB2 receptors to bring you to a healthy state of balance.

NATIVE ROOTS HEMP. SUPPORTING WI FARMERS. ORGANICALLY GROWN HEMP.

Located in downtown De Pere, WI, with a licensed kitchen and private outdoor patio, Native Roots Hemp offers everything from Hemp/CBD and Delta 8 edibles and smokables to premium skincare products. They have what you’re looking for. And don’t forget your furry-friend! Native Roots Hemp also offers calming dog treats and pet oil. Native Roots Hemp prides itself on our one-on-one customer service, assisting you in choosing the right hemp/CBD product for you. Whether you’re beauty-obsessed, a fitness-enthusiast, just looking to destress or a senior, there is a hemp product for you.

Contact us at 920-487-8788, and learn more or order online with free delivery at nativerootshemp.com

Caffe Tlazo in Algoma Offers Native Roots Hemp
Caffe Tlazo is Comfy and CozyCaffe Tlazo is Comfy and Cozy

What’s the Scoop on Delta-8

How does Delta-8 make you feel?

According to Mercury News:  The effects of Delta8 THC and the traditional Delta-9 THC are fairly similar, but the potency of Delta8 is what sets it apart from its highly psychoactive counterpart. Delta8 can make you feel high, but it is thought to create a milder effect.

When combined with cannabinoids such as CBN (typically reportedly used for anxiety or sleep) the D8 has different effects.  Use it with CBD for a milder euphoric sensation.

And, while we don’t judge, millions of people choose to drink each week throughout America. Many of them suffer hangovers. And, while a high quality plant, such as a hemp plant is thought to lessen the after-effects of an alcohol-induced night out, users of Delta-8 THC report a euphoric feeling without the hangover.

How long will the effects of Delta-8 THC last?

Consumers report effects of Delta-8 can last anywhere from 3 – 8 hours.

Is Delta-8 Legal in Wisconsin?

According to Kush, a substance meeting the definition of “hemp” is legal for purposes of state and federal controlled substances laws regardless of its Delta 8-THC concentration.  This means that any hemp-derived Delta 8 THC that has less than .3% of Delta 9 THC is legal. 

The short answer is “yes.”

How to Incorporate CBD Into Your Chiropractic Practice

As a chiropractor, it’s important to keep up to date with industry trends to ensure you are offering patients a comprehensive approach to treatment. Over the past few years, topical cannabidiol (CBD) products have grown in popularity, especially in the chiropractic market1as they have been linked to alternative relief for sore muscles and joints. With so many hemp-derived CBD products on the market, it can be difficult to choose the right ones for your patients and practice. 

Let’s dive into the steps you can take to begin incorporating CBD products into your practice. 

Legalization & CBD

When the  Agricultural Improvement Act of 2018 AKA 2018 Farm Bill was passed, it removed “hemp” from the definition of “marijuana”, so long as the THC concentration does not exceed 0.3 percent.Despite the fact that on a federal level, hemp crop regulation is in the hands of the U.S. Department of Agriculture, the legislation preserved the FDA’s responsibility over such products.3 For chiropractors looking to incorporate CBD products into their practice, it is crucial to understand the legal status of CBD in your state of practice so that you are acting in line with the law.

Do I Need a License to Sell CBD at My Practice? 

The 2018 Farm Bill recognizes the federal legalization of hemp-derived CBD in the United States—but not statewide regulations about CBD, which vary by state. Before integrating CBD into your practice, research your state’s laws regarding hemp-derived CBD.

In terms of a license, your chiropractic practice should have a business license, as well as a seller’s permit if you intend to sell any products to patients in your practice.4 This type of permit is handled on the state level, so refer to your local or state government for guidance on obtaining a seller’s permit for your chiropractic practice. 

At MeyerDC, we sell topical, hemp-derived CBD products to chiropractors in the following states: Alabama, California, Florida, Georgia, Illinois, Indiana, Kentucky, Michigan, Nevada, Ohio, Oregon, South Carolina, Tennessee, Wisconsin, and Washington. This is changing frequently due to state regulations on CBD, so check individual products for their availability in your state. 

 

 

Earth Power: Hemp Batteries Better Than Lithium And Graphene

By Barnaby De Hoedt

Henry Ford’s Model T was famously made partly from hemp bioplastic and powered by hemp biofuel. Now, with battery-powered vehicles starting to replace those that use combustion engines, it has been found that hemp batteries perform eight times better than lithium-ion. Is there anything that this criminally-underused plant can’t do?

The comparison has only been proven on a very small scale. (You weren’t expecting a Silicon Valley conglomerate to do something genuinely groundbreaking were you? They mainly just commercialise stuff that’s been invented or at least funded by the state.) But the results are extremely promising.

The experiment was conducted by Robert Murray Smith – who has built up quite a following on his YouTube channel – of FWG Ltd in Kent. He observed a Volts by Amps curve of both the hemp and lithium batteries and found that the power underneath the hemp cell was a value of 31 while that of the lithium cell had a value of just 4. Although he does not claim to have proven anything, he said that the results of his experiment showed that the performance of the hemp cell is “significantly better” than the lithium cell.

It comes as no real surprise, which is presumably why he conducted the experiment. In 2014, scientists in the US found that waste fibers – ‘shiv’ – from hemp crops can be transformed into “ultrafast” supercapacitors that are “better than graphene”. Graphene is a synthetic carbon material lighter than foil yet bulletproof, but it is prohibitively expensive to make. The hemp version isn’t just better, it costs one-thousandth of the price.

The scientists “cooked” leftover bast fibre – the inner bark of the plant that usually ends up in landfill – into carbon nanosheets in a process called hydrothermal synthesis. “People ask me: why hemp? I say, why not?” said Dr David Mitlin of Clarkson University, New York, in an interview with the BBC. “We’re making graphene-like materials for a thousandth of the price – and we’re doing it with waste.”

Dr. Mitlin’s team recycled the fibers into supercapacitors, energy storage devices that are transforming the way electronics are powered. While conventional batteries store large reservoirs of energy and drip-feed it slowly, supercapacitors can rapidly discharge their entire load.

This makes them ideal in machines that require sharp bursts of power. In electric cars, for example, supercapacitors are used for regenerative braking. Releasing this torrent requires electrodes with high surface area, one of graphene’s many phenomenal properties.

Mitlin says that “you can do really interesting things with bio-waste”. With banana peels, for example, “you can turn them into a dense block of carbon – we call it pseudo-graphite – and that’s great for sodium-ion batteries. But if you look at hemp fibre its structure is the opposite – it makes sheets with high surface area – and that’s very conducive to supercapacitors.”

 

The Benefits Of Using Hemp In The Construction And Textile Industries

Ever since the cannabis legalization process began to gain global momentum, much has been said about its medicinal and therapeutic potential, as well as the huge market that awaits behind the doors of adult-use regulation.

However, the cannabis plant has even greater potential, of which today we’re seeing but the tip of the iceberg. Hemp is a subspecies of the cannabis plant; it lacks most of marijuana’s psychoactive effects but can be used as raw material for several industries -such as textile and construction.

In fact, industrial sales are expected to triple in the next 7 years, rising from $4.71 billion in 2019 to $15.26 billion in 2027.

Reducing The Carbon Footprint

Steve DeAngelo, one of the most recognized cannabis activists of the last decades, says that hemp has the ability to replace virtually any petroleum product. 

“Hemp can be grown without pesticides. Captures 22 tons of atmospheric carbon per hectare. It is a powerful phytoremediator that extracts industrial poisons from contaminated soil. And, likewise, it is a powerful tool to control erosion and remedy unproductive or marginally productive lands,” says DeAngelo. And adds: “We are only now harnessing the industrial hemp plant’s potential as a rotating crop with regenerative agriculture qualities.”

The Textile Industry

Hemp fabric has been around for a long time, from Rembrandt’s canvases to the sails in Columbus’s caravels. Now, the textile industry is strongly experiencing hemp’s disruption, especially as a replacement for cotton.

The material can be processed to be lightweight, soft, breathable, and durable, replacing most cotton applications in the textile industry. Considering that cotton represents 43% of all fibers used for clothing and textiles worldwide, hemp has huge possibilities ahead.

For instance, iconic jeans company Levi’s recently announced a pilot project to replace 27% of its denim’s cotton with hemp, as part of an overall sustainability push. Why? Cotton requires much more water, pesticides, and soil to be grown than hemp.

 

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