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Study shows hemp compounds prevent coronavirus from entering human cells

Laboratory research is a collaboration of researchers at OHSU, Oregon State University
Study shows hemp compounds prevent coronavirus from entering human cells. Hemp growing in a field amid the dawn.

“The study’s implication is that some hemp-based consumer products have the potential to prevent as well as treat infection from the novel coronavirus,” said senior author Fikadu Tafesse, Ph.D., assistant professor of molecular microbiology and immunology in the OHSU School of Medicine. (Getty Images)

New research reveals compounds in hemp demonstrate an ability to prevent the virus that causes COVID-19 from entering human cells.

The study, published in the Journal of Natural Products, was a collaboration between scientists at Oregon Health & Science University and Oregon State University.

The laboratory study used chemical screening techniques to discover that a pair of distinct cannabinoid acids in hemp — known as cannabigerol acid, or CBGA, and cannabidiolic acid, or CBDA — bind to the SARS-CoV-2 spike protein, blocking a critical step in the process the virus uses to infect people.

Fikadu Tafesse Ph.D. (OHSU), a tall man with dark hair smiling in the Vollum courtyard at OHSU.

Fikadu Tafesse, Ph.D. (OHSU)

“This is a lab study, so it hasn’t been tested clinically,” said senior author Fikadu Tafesse, Ph.D., assistant professor of molecular microbiology and immunology in the OHSU School of Medicine. “However, the study’s implication is that some hemp-based consumer products have the potential to prevent as well as treat infection from the novel coronavirus.”

Known scientifically as Cannabis sativa, hemp is a source of fiber, food, and animal feed. Hemp extracts and compounds are also added to cosmetics, body lotions, and dietary supplements.

The study was led by Richard van Breeman, Ph.D., a researcher with Oregon State’s Global Hemp Innovation Center, College of Pharmacy, and Linus Pauling Institute.

In addition to Tafesse and van Breeman, co-authors include Ruth Muchiri of Oregon State, along with Timothy BatesJules WeinsteinHans Leier, and Scotland Farley of OHSU.

For more information, see the news release from Oregon State University: https://today.oregonstate.edu/news/oregon-state-research-shows-hemp-compounds-prevent-coronavirus-entering-human-cells

 

Article Credits

How Mainstream Media Botched the Vape Lung Story

David Bienenstock

In 1989, a mysterious figure known as Dr. Lunglife sent High Times a set of detailed instructions for transforming a handful of easily obtained equipment into a low cost vaporizer. He included a guide to making a highly potent cannabis concentrate that optimized the contraption’s effectiveness.

Soon thereafter, the magazine published a letter to the editor from K.O. of Clarksville, Mississippi:

Just thought I’d let you know I built one of Dr. Lunglife’s vaporizers. Tell the good doctor that it has worked well for me. Now if I can just get a really long extension cord for the Hash Bash in Ann Arbor.

30 years of user data on vaping

Clearly, many cannabis enthusiasts must have started experimenting with vaporization around this same time.

Commercial products required a little more time to make it to market. The first Volcano vaporizer, made by Storz & Bickel, appeared in the US in 2003. The first pen-size vaporizers appeared around 2006. Cannabis vape pens hit the American scene starting around 2010.

That gives us—at the very least—a solid three decades of anecdotal user data to work with when evaluating any potential harms involved.

So when a rash of people started getting seriously or even fatally ill after using vape pens earlier this year, it was obvious that something other than cannabis must be the culprit. The overwhelming number of cases of VAPI, vaping associated pulmonary injury, have been attributed to counterfeit products produced and distributed illegally without any regulatory oversight whatsoever.

Tainted illegal THC pens are suspect

At Leafly, our reporting team tracked these dangerous counterfeit pens from production to sale. We found a supply chain operating wholly outside the law and with a blatant disregard for public health. Theories on what’s causing VAPI range from dangerous additives to poorly manufactured pens, or possibly some combination of the two. No evidence has emerged to show THC, CBD, or any other cannabinoid is to blame.

 

 

 

Why CBG (Cannabigerol) Is One Of The Most Expensive Cannabinoids To Produce

As CBD continues to explode in popularity, brands are beginning to take notice. Innovative companies are already beginning to offer products centered around one of the other 100+ cannabinoids found in the plant.

One of those cannabinoids is Cannabigerol, or CBG. First discovered by researchers in the 1960’s, CBG is the precursor from which all other cannabinoids are synthesized, which is why it’s often referred to as the “mother” or “stem cell” of cannabinoids. This unique property imbues CBG with enormous therapeutic promise, making it a subject of great interest for researchers and consumers alike.

“It’s definitely gaining momentum,” says James Rowland, CEO of Steve’s Goods, a Colorado based brand that specializes in producing CBG goods. “We have personally administered CBG to thousands of people at over 50 events. It’s the most requested product on our website and we provide education to thousands of receptive people both in person and online every month.”

CBG (Cannabigerol) being made

CBG (Cannabigerol) being made PHOTOS COURTESY OF STEVE’S GOODS

The US government is also keen on learning more about CBG. In 2018 The National Center for Complementary and Integrative Health (NCCIH) announced an intent to research minor cannabinoids including CBG that could help manage pain. Today In: Lifestyle

So how exactly does CBG work?

“CBG works by interacting with the endocannabinoid system (ECS). Together, CB1 and CB2 receptors regulate neurohormones which actively affect physiological processes including mood, metabolism, pain response, and appetite,” begins Derek Du Chesne, Chief Growth Officer at EcoGen Laboratories. “When cannabinoids like CBG interact with these receptors, it activates a response and produces physiological changes.”

 

 

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